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Tamoxifen

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Dosage Package Price per pill, $ Price, $ Buy
10mgX20 20 0.30 6.00
10mgX30 30 0.25 7.50
10mgX60 60 0.23 13.80
10mgX90 90 0.21 18.90
10mgX120 120 0.19 22.80
10mgX180 180 0.17 30.60
10mgX270 270 0.15 40.50
10mgX360 360 0.14 50.40
20mgX20 20 0.76 15.20
20mgX30 30 0.67 20.10
20mgX60 60 0.61 36.60
20mgX90 90 0.55 49.50
20mgX120 120 0.49 58.80
20mgX180 180 0.44 79.20
20mgX270 270 0.40 108.00

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No Prescription

Tamoxifen is prescribed for the treatment of breast cancer.
Tamoxifen is prescribed to:

* treat breast cancer that has spread to other parts of the body in men and women.
* treat early breast cancer in women who have already been treated with surgery, radiation, and/or chemotherapy.
* reduce the risk of developing a more serious type of breast cancer in women who have had ductal carcinoma in situ (DCIS; a type of breast cancer that does not spread outside of the milk duct where it forms) and who have been treated with surgery and radiation.
* reduce the risk of breast cancer in women who are at high risk for the disease due to their age, personal medical history, and family medical history.

Tamoxifen is in a class of prescriptions known as antiestrogens. It blocks the activity of estrogen (a female hormone) in the breast. This may stop the growth of some breast tumors that need estrogen to grow.

Tamoxifen is usually taken once or twice a day with or without food. Take tamoxifen at around the same time(s) every day.

Swallow tamoxifen tablets whole; do not split, chew, or crush them. Swallow the tablets with water or any other nonalcoholic drink.

If you are taking tamoxifen to prevent breast cancer, you will probably take it for five years. If you are taking tamoxifen to treat breast cancer, your doctor will decide how long your treatment will last. Do not stop taking tamoxifen without talking to your doctor.

If you forget to take a dose of tamoxifen, take the missed dose as soon as you remember it, and take your next dose as usual. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

One of the selective estrogen receptor modulators with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue, but as an estrogen (stimulating agent) in cholesterol metabolism, bone density, and cell proliferation in the endometrium.

Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators (SERMs), which have both estrogenic and antiestrogenic effects. Tamoxifen has the same nucleus as diethylstilbestrol but possesses an additional side chain (trans isomer) which accounts for its antiestrogenic activity.

Contraindications

Tamoxifen is contraindicated in patients with known hypersensitivity to the drug or any of its ingredients.
Reduction in Breast Cancer Incidence in High Risk Women and Women with DCIS:
Tamoxifen is contraindicated in women who require concomitant coumarin-type anticoagulant therapy or in women with a history of deep vein thrombosis or pulmonary embolus.

Side Effects

Tamoxifen side effects that you should report to your health care professional or doctor as soon as possible:
- blisters;
- constipation;
- depression;
- dizziness;
- excessive tiredness;
- fever;
- headache;
- hot flashes;
- increased bone or tumor pain;
- loss of appetite;
- loss of sexual desire or ability (in men);
- muscle weakness;
- nausea;
- pain or reddening around the tumor site;
- rash;
- restlessness;
- stomach cramps;
- swelling of the eyes, face, lips, tongue, throat, hands, arms, feet, ankles, or lower legs;
- thinning of hair;
- thirst;
- uncontrollable shaking of a part of the body;
- unsteadiness;
- unusual bruising or bleeding;
- vision problems;
- weight loss;
- yellowing of the skin or eyes;
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