Tacrolimus no prescription

 Tacrolimus without a prescription

      No Prescription, Without a Prescription.



Main information about Tacrolimus

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Tacrolimus

Buy Tacrolimus online. Compare Prices

Dosage Package Price per pill, $ Price, $ Buy
0,5mgX10 10 2.72 27.20
0,5mgX20 20 2.18 43.60
0,5mgX30 30 1.96 58.80
0,5mgX60 60 1.76 105.60
0,5mgX90 90 1.59 143.10
1mgX10 10 3.78 37.80
1mgX20 20 3.02 60.40
1mgX30 30 2.72 81.60
1mgX60 60 2.45 147.00
1mgX90 90 2.20 198.00
5mgX10 10 24.08 240.80
5mgX20 20 20.53 410.60

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No Prescription

Tacrolimus is prescribed for use after allogenic organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It was first approved by the FDA in 1994 for use in liver transplantation, this has been extended to include kidney, heart, small bowel, pancreas, lung, trachea, skin, cornea, and limb transplants. It has also been used in a topical preparation in the treatment of severe atopic dermatitis.
Tacrolimus is prescribed to prevent rejection of liver transplants. Sometimes it is prescribed to prevent rejection of other types of transplants.

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex interacts with and inhibits calcineurin thus inhibiting both T-lymphocyte signal transduction and IL-2 transcription.

Contraindications

Tacrolimus is contraindicated in patients with a history of hypersensitivity to tacrolimus or any other component of the preparation.

Without a Prescription

Tacrolimus comes as a capsule to take by mouth and in an injectable form. It usually is taken twice a day.

Tacrolimus is a macrolide antibiotic. It acts by reducing peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This inhibits both T-lymphocyte signal transduction and IL-2 transcription. Although this activity is similar to cyclosporine studies have shown that the incidence of acute rejection is reduced by tacrolimus use over cyclosporine. Tacrolimus has also been shown to be effective in the topical treatment of eczema, particularly atopic eczema. It suppresses inflammation in a similar way to steroids, but is not as powerful. An important dermatological advantage of tacrolimus is that it can be used directly on the face; topical steroids cannot be used on the face, as they thin the skin dramatically there. On other parts of the body, topical steroid are generally a better treatment.

Side Effects

Tacrolimus side effects that you should report to your health care professional or doctor as soon as possible:
- chills;
- decreased urination;
- diarrhea;
- difficulty breathing;
- fever;
- frequent or painful urination;
- hives;
- insomnia;
- itching;
- loss of appetite;
- seizures;
- severe or continued headaches;
- skin rash;
- sore throat;
- stomach pain;
- swelling of the feet, ankles, lower legs, and hands;
- tremor;
- unusual bleeding or bruising;
- upset stomach;
- vomiting;
- weakness;
- weight gain;
- wheezing;
- yellowing of the skin or eyes;
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No Prescription, Without a Prescription