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Fluticasone is prescribed for partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome.
Fluticasone oral inhalation is prescribed to prevent difficulty breathing, chest tightness, wheezing and coughing caused by asthma. Fluticasone is in a class of prescriptions called corticosteroids. It works by decreasing swelling and irritation in the airways to allow for easier breathing.
A synthetic mineralocorticoid with anti-inflammatory activity.
Corticosteroids are contraindicated in patients with systemic fungal infections and in those with a history of possible or known hypersensitivity to these agents.
Without a Prescription
Fluticasone comes as an aerosol to inhale by mouth. Fluticasone is usually inhaled twice a day. Try to use fluticasone at around the same times every day.
Talk to your doctor about how you should use your other oral and inhaled prescriptions for asthma during your treatment with fluticasone inhalation. If you were taking an oral steroid such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), or prednisone (Deltasone), your doctor may want to gradually decrease your steroid dose starting at least 1 week after you begin to use fluticasone. Special care will be needed in certain situations for several months as your body adjusts to the change in prescription. Ask your doctor for more information.
Fluticasone helps to prevent asthma attacks (sudden episodes of shortness of breath, wheezing, and coughing) but will not stop an asthma attack that has already started. Do not use fluticasone during an asthma attack. Your doctor will prescribe a short-acting inhaler to use during asthma attacks.
Your doctor will probably start you on an average dose of fluticasone. Your doctor may decrease your dose when your symptoms are controlled or increase it if your symptoms have not improved after at least 2 weeks.
Fluticasone controls asthma but does not cure it. Your symptoms may improve 24 hours after you begin using fluticasone, but it may take 2 weeks or longer before you feel the full benefit of the prescription. Continue to use fluticasone even if you feel well. Do not stop using fluticasone without talking to your doctor.
Tell your doctor if your asthma worsens during your treatment. Call your doctor if you have an asthma attack that does not stop when you use your fast acting asthma prescription, or if you need to use more of your fast acting prescription than usual.
The inhaler that comes with fluticasone aerosol is designed for use only with a canister of fluticasone. Never use it to inhale any other prescription, and never use any other inhaler to inhale fluticasone.
Each canister of fluticasone aerosol is designed to provide 60 or 120 inhalations, depending on its size. After the labeled number of inhalations has been used, later inhalations may not contain the correct amount of prescription. You should keep track of the number of inhalations you have used. You can divide the number of inhalations in your inhaler by the number of inhalations you use each day to find out how many days your inhaler will last. Throw away the canister after you have used the labeled number of inhalations even if it still contains some liquid and continues to release a spray when it is pressed. Do not float the canister in water to see if it still contains prescription.
Before you use your fluticasone aerosol inhaler the first time, read the written instructions that come with it. Look at the diagrams carefully and be sure that you recognize all the parts of the inhaler. Ask your doctor, pharmacist, or respiratory therapist to show you how to use it. Practice using the inhaler while he or she watches.
Do not use your fluticasone inhaler while you are near an open flame or a heat source. The inhaler may explode if it is exposed to very high temperatures.
To use the aerosol inhaler, follow these steps:
- Be sure that the inhaler is at room temperature.;
- Be sure the canister is fully and firmly inserted in the actuator. Shake the inhaler well for 5 seconds.;
- Before you use the inhaler for the first time, remove it from the overwrap. Throw away the overwrap and the drying packet that is inside the overwrap.;
- Breathe in deeply and slowly through your mouth. At the same time, press down firmly on the top of the canister with your index finger. Remove your index finger as soon as the spray is released.;
- Breathe out through your mouth.;
- Hold the inhaler facing you with the mouthpiece on the bottom. Place your thumb under the mouthpiece and your index finger on the top of the canister. Place the mouthpiece in your mouth and close your lips around it.;
- If you are using the inhaler for the first time, prime it by releasing 4 test sprays into the air, away from your face. Shake the inhaler for 5 seconds before each spray. If you have not used the inhaler in more than 7 days, or if you have dropped the inhaler, shake the inhaler for 5 seconds and release one spray into the air. Be careful not to spray the prescription into your eyes.;
- If your doctor told you to inhale more than one puff, wait 30 seconds, shake the canister again, and repeat steps 6-10 for each puff.;
- Put the cap back on the mouthpiece.;
- Remove the cap from the mouthpiece. The strap on the side of the cap will stay attached to the actuator to keep the cap from getting lost. Check the mouthpiece for dirt and other objects before each use, especially if the cap was not used to cover the mouthpiece.;
- Rinse your mouth with water and spit the water out. Do not swallow the water.;
- Try to hold your breath for 10 seconds.;
- When you have breathed in fully, remove the inhaler from your mouth and close your mouth.;
Clean your inhaler once a week after an evening dose. To clean your inhaler, follow these steps:
- Dampen a clean tissue with water. Wipe the inside of the mouthpiece with the damp tissue.;
- Dampen the tip of a cotton swab with water. Use the damp swab to clean the small hole where the prescription comes out. Twist the swab in a circular motion to remove any prescription that is left in or near the hole.;
- Leave the mouthpiece uncovered overnight to allow it to air dry.;
- Remove the mouthpiece cap, but leave the canister in the actuator.;
- Repeat step 2 with a second cotton swab.;
- Replace the mouthpiece cap when the actuator is dry.;
Fluticasone is a synthetic adrenocortical steroid possessing very potent mineralocorticoid properties and high glucocorticoid activity. It is prescribed as partial replacement therapy for primary and secondary adrenocortical insufficiency in Addison's disease and for the treatment of salt-losing adrenogenital syndrome. The physiologic action of fludrocortisone acetate is similar to that of hydrocortisone. However, the effects of fludrocortisone acetate, particularly on electrolyte balance, but also on carbohydrate metabolism, are considerably heightened and prolonged. Mineralocorticoids act on the distal tubules of the kidney to enhance the reabsorption of sodium ions from the tubular fluid into the plasma; they increase the urinary excretion of both potassium and hydrogen ions.
Fluticasone side effects that you should report to your health care professional or doctor as soon as possible:
- burning, tingling, numbness, or weakness in arms or legs;
- chest pain or tightness;
- darkening of skin;
- difficulty breathing or swallowing;
- difficulty speaking;
- easy bruising;
- enlarged face and neck;
- extreme tiredness;
- fainting or dizziness when standing up from a sitting or lying position;
- growth of hair on the face;
- irregular menstrual periods;
- irregular menstruation (periods);
- loss of appetite;
- muscle weakness;
- new or increased acne (pimples);
- new or worsening acne;
- painful white patches in the mouth or throat+;
- pink or purple stretch marks on the skin;
- red or fluid filled bumps on skin;
- shortness of breath;
- sore or irritated throat;
- stuffy or runny nose;
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs;
- weight loss;